The Medical Skin ClinicMedHub
All articles

Treatments · 11 July 2025

Profhilo® Structure: A Natural Treatment for ‘Ozempic Face’

Profhilo® Structure: A Natural Treatment for ‘Ozempic Face’

GLP-1 medications like Ozempic® and Wegovy® have revolutionised weight loss. But for some, rapid fat loss—especially in the face—can result in an aged, hollow appearance known as Ozempic Face . At The Medical Skin Clinic in Newmarket, we offer Profhilo® Structure , an advanced injectable treatment designed to restore facial structure, boost skin quality, and rejuvenate your natural appearance without looking “done”.

What Is Ozempic Face?

“Ozempic Face” is a term used to describe the loss of facial fat and skin firmness that can follow significant weight loss—particularly in patients using medications like Ozempic® (semaglutide) . This loss of subcutaneous fat and collagen can lead to:

  • Sunken or flattened cheeks

Sunken or flattened cheeks

  • Hollow temples

Hollow temples

  • Loose or sagging skin

Loose or sagging skin

  • Deeper nasolabial folds and jowls

Deeper nasolabial folds and jowls

  • A tired or prematurely aged look

A tired or prematurely aged look

These changes are especially noticeable in people over 35, when natural collagen production is already declining.

How Profhilo® Structure Works

Profhilo® Structure is the newest formulation in the Profhilo range, uniquely designed to rebuild lost structure in the mid and lower face. It combines ultra-pure hyaluronic acid with bio-remodelling properties to stimulate collagen, elastin, and deep hydration—helping to lift and firm the skin from within.

Key benefits of Profhilo Structure include:

✅ Skin tightening without added bulk

✅ Improved skin density and support

✅ Enhanced hydration and elasticity

✅ Subtle, natural-looking results

✅ No downtime, minimal discomfort

Unlike dermal fillers, which replace volume directly, Profhilo® Structure rebuilds your skin’s own ability to support itself , making it ideal for those experiencing skin thinning or hollowing from weight loss.

Profhilo Structure vs Traditional Profhilo

While standard Profhilo is already a popular choice for skin quality and hydration, Profhilo Structure is designed specifically to address facial sagging and structural loss . This makes it a superior option for:

  • Ozempic Face

Ozempic Face

  • Midface hollowing

Midface hollowing

  • Age-related volume depletion

Age-related volume depletion

  • Sagging jawline and skin laxity

Sagging jawline and skin laxity

It can also be combined with targeted dermal fillers or skin boosters for enhanced facial rejuvenation.

What to Expect During Treatment

Treatment with Profhilo Structure is quick, comfortable, and non-invasive:

  • Administered via a series of small injections

Administered via a series of small injections

  • Treatment takes approximately 15–20 minutes

Treatment takes approximately 15–20 minutes

  • Minimal downtime – you can resume normal activity straight away

Minimal downtime – you can resume normal activity straight away

  • Mild swelling or bruising may occur and settle within 1–2 days

For optimal results, two sessions are typically recommended four weeks apart , followed by maintenance every 4–6 months.

Who Is a Good Candidate?

Profhilo Structure is ideal if you:

  • Have experienced rapid weight loss (e.g. from Ozempic or Wegovy)

Have experienced rapid weight loss (e.g. from Ozempic or Wegovy)

  • Are noticing sagging, hollowing, or skin thinning in the face

Are noticing sagging, hollowing, or skin thinning in the face

  • Prefer natural-looking, subtle aesthetic results

Prefer natural-looking, subtle aesthetic results

  • Are new to injectables and want a gentle, restorative treatment

Are new to injectables and want a gentle, restorative treatment

At The Medical Skin Clinic , every treatment begins with a thorough consultation. Our medical practitioners will assess your concerns and create a personalised plan that may include Profhilo Structure alone or in combination with other rejuvenating options.

Book Your Consultation at The Medical Skin Clinic, Newmarket

If you're concerned about facial volume loss, sagging skin, or a tired appearance after weight loss, Profhilo® Structure offers a safe, effective, and natural solution .

📍 Located in Newmarket, Suffolk

💉 Medical-led aesthetic treatments

💬 Confidential consultations with experienced clinicians

Restore confidence in your reflection . Book your consultation online at www.medicalskinclinic.co.uk or call our team to learn more about Profhilo for Ozempic Face.

Questions about your own skin? A consultation with our medical team is the right place to start.

Book a consultation

More in Treatments

All articles